Endocrine Abstracts

Introduction: Pituitary apoplexy (PA) is a syndrome caused by acute hemorrhage or infarction of the pituitary gland, generally within a pituitary adenoma. Early diagnosis of PA and a multidisciplinary approach are essential for the timely treatment of pan-hypopituitarism and prevention of severe neurologic complications.Observation: We report the cases of two men aged 46 and 53 years old with pituitary apoplexy. Apoplexy occurred in one patient with pre-...

Introduction: Acromegaly is a rare and misdiagnosed disease characterized by somatotropic hypersecretion. The purpose of this study is to describe the epidemiological, clinical, para-clinical, therapeutic features of Acromegaly disease.Patients and methods: This is a retrospective study including 10 patients with acromegaly in the Endocrinology Diabetology Department of Oujda’s Mohammed VI University Hospital, Morocco.Results:...

Introduction: Somatostatinanalogues (SSAs) are the largest contributor to the direct medical cost of acromegaly management worldwide. The aim of this review was to expose our experience and report available evidence on the effectiveness of SSAs in the treatment of acromegaly.Methods: This is a retrospective study including ten acromegalic patients followed in the Endocrinology - Diabetology Department at Mohamed VI University Hospital in Oujda, Morocco.<...

Introduction: 46 XY sex development disorders are a group of rare congenital conditions in which chromosomal, gonadal or anatomic sex is atypical. Less than 20% of cases have a precise genetic diagnosis. We report here the case of a patient suffering from a 46 XY sexual development disorder secondary to the MAMLD 1 gene mutation.Observation: The patient is a nine month infant who was admitted for abnormalities of the external genital organs. The physical...

Introduction: Besides its role in calcium homeostasis, vitamin D (VD) has an important immune mudulation effect. However, its role in autoimmune diseases such as type 1 diabetes is under discussion. In this study, we aimed to assess VD status in children and adolescents with type 1 diabetes mellitus (T1DM).Material and Methods: This is a retrospective descriptive study realized at the endocrinology–diabetology department of OUJDA’s Mohammed V...